LDL Reduction Unit

Head: Genovefa Kolovou
Associate Doctor: Giorgos Chatzigeorgiou
Nurse: Nikolaos Gondoras

In 2015, the first LDL Unit in Greece was created, certifying the work that has been applied at the Onassis Cardiac Surgery Center for 12 years. The first LDL Reduction was performed at the OCSC in 2003, while LDL reduction sessions had been performed overseas for more than two decades. The objective is to reduce the levels of LDL cholesterol in plasma. The reduction may be up to 80%.

Up to the present time, there are three categories of patients with the need for LDL reduction sessions:

  1. People with homozygous familial hypercholesterolemia, in whom the total cholesterol remains above 350mg/dl, or the decline was less than 50%, despite the provision of allowable higher doses of lipid-lowering drugs.
  2. Individuals with familial hypercholesterolemia and deterioration of coronary disease, in whom the total cholesterol remains above 190mg/dl, or the reduction was less than 40%, despite the provision of allowable higher doses of hypolipidemic drugs.
  3. Only as an exception, patients with lipoprotein (a) more than 60mg/dl and exacerbation of cardiovascular disease, in whom LDL cholesterol remains above 120mg/dl, despite the provision of allowable higher doses of lipid-lowering drugs.

The procedure is similar to dialysis, but without mounted fistula (connection between artery and vein leading to increase blood flow through the vein).

The patients’ age range from 11-70 years. From December 2015 LDL reduction sessions are performed also for younger children.

The frequency of session depends on the patients’ condition and response.